Terlipressin Injection 1 mg / 0.10 mg

  • synthetic triglycyl-lysine derivative
  • inactive prodrug
Category:

Description

Terlipressin  Injection 1 mg / 0.10 mg  is a synthetic triglycyl-lysine derivative of vasopressin, is a inactive prodrug. It has pressor and antidiuretic effects. It is used in posterior pituitary lobe hormone preparations and is an analogue of vasopressin used as a vasoactive drug in the management of low blood pressure. It has been found to be effective when norepinephrine does not help.So it is used in norepinephrine-resistant septic shock and hepatorenal syndrome. In addition, it is used to treat bleeding esophageal varices.Following IV injection, lysine vasopressin are released following the enzymatic cleavage of 3 glycyl moieties. Terlipressin acetate 0.12 mg/ml solution for injection is used for treatment of bleeding from dilated veins in the food pipe leading to your stomach (bleeding oesophageal varices).

India has many manufacturers who manufacture Terlipressin  Injection 1 mg / 0.10 mg .To know more contact us.

3s corporation is Supplier,Exporter ,Wholesaler  for Terlipressin  Injection 1 mg / 0.10 mg in India.

Additional Information

Adult: Initially, 2 mg followed by 1 or 2 mg every 4-6 hr until bleeding is controlled, for up to 72 hr.

This medicine must not be used during pregnancy.

Side Effects

Severe shortness of breath due to an asthma attack, severe difficulty with or stopping breathing, severe pain in the chest (angina), severe and persistent irregular heartbeats, locally dead skin (necrosis), convulsions (seizure), kidney failure.

Other possible side effects

Common (affects less than 1 in 10 people)

– headache

– too slow heart rate

– signs of insufficient blood circulation in the heart vessels shown in the ECG

– high blood pressure

– low blood pressure

– insufficient blood circulation in arms, legs and skin,

pale skin

– abdominal cramps

– diarrhoea

Uncommon (affects less than 1 in 100 people)

– too little sodium in the blood (hyponatraemia)

– rapid increase in blood pressure

– too fast heart rate (palpitations)

– chest pain

– heart attack

– excess fluid on the lungs

– insufficient blood flow to the intestines

– bluish colouration of the skin or lips

– hot flushes

– temporary nausea (feeling sick)

– temporary vomiting

– inflammation of the lymph vessels .

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