Ibandronic Acid Tablets is used in Treatment of osteoporosis in postmenopausal women at increased risk of fracture.A reduction in the risk of vertebral fractures has been demonstrated, efficacy on femoral neck fractures has not been established.Ibandronic acid is a highly potent bisphosphonate belonging to the nitrogen-containing group of bisphosphonates, which act selectively on bone tissue and specifically inhibit osteoclast activity without directly affecting bone formation. It does not interfere with osteoclast recruitment. Ibandronic acid leads to progressive net gains in bone mass and a decreased incidence of fractures through the reduction of elevated bone turnover towards premenopausal levels in postmenopausal women.
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The recommended dose is one 150 mg film-coated tablet once a month. The tablet should preferably be taken on the same date each month.
Ibandronic acid should be taken after an overnight fast (at least 6 hours) and 1 hour before the first food or drink (other than water) of the day or any other oral medicinal products or supplementation (including calcium).
In case a dose is missed, patients should be instructed to take one ibandronic acid 150 mg tablet the morning after the tablet is remembered, unless the time to the next scheduled dose is within 7 days. Patients should then return to taking their dose once a month on their originally scheduled date.
Tablets should be swallowed whole with a glass of plain water (180 to 240 ml) while the patient is sitting or standing in an upright position. Patients should not lie down for 1 hour after taking ibandronic acid.
Plain water is the only drink that should be taken with ibandronic acid. Please note that some mineral waters may have a higher concentration of calcium and therefore, should not be used.