Body as a Whole:Fever,asthenia,fatigue.
Cardiovascular: arrhythmia, AV block, palpitation
Gastrointestinal: cholestatic jaundice, liver enzyme abnormalities, vomiting,nausea, abdominal discomfort,anorexia, dry mouth.
Musculoskeletal: musculoskeletal pain including muscle cramps, arthralgia.
Nervous System/Psychiatric: grand mal seizure; psychic disturbances, which were reversible in cases for which follow-up was obtained, including hallucinations, confusion, agitation, depression, anxiety, decreased libido;paresthesia; insomnia; somnolence. Convulsions, in patients with impaired renal function, have been reported very rarely.
Respiratory: bronchospasm, interstitial pneumonia
Skin: toxic epidermal necrolysis/Stevens Johnson syndrome (very rare),acne, dry skin, flushing
Special Senses: tinnitus, taste disorder