Evermil (Everolimus) Tablet is prescription drug used in treatment of breast cancer, pancreatic cancer, lung cancer and kidney cancer. EVERMIL is an immunosuppressant , ie, It suppresses the activity of body’s immune system that may cause the body to reject the transplanted organ.
Manufacturer : Glenmark Pharmaceuticals Ltd
Strengths available : 5mg & 10mg
Storage : Store at temperature between 15°C – 25°C
Patients receiving Evermil may require dose adjustments based on Evermil blood concentrations achieved, tolerability, individual response, change in concomitant medications and the clinical situation.
Dosage in Adult Kidney Transplant Patients
An initial Evermil dose of 0.75 mg orally twice daily (1.5 mg per day) is recommended for adult kidney transplant patients in combination with reduced dose cyclosporine, administered as soon as possible after transplantation. Oral prednisone should be initiated once oral medication is tolerated. Steroid doses may be further tapered on an individualized basis depending on the clinical status of patient and function of graft.
Dosage in Adult Liver Transplant Patients
Start Evermil at least 30 days post-transplant. An initial dose of 1.0 mg orally twice daily (2.0 mg per day) is recommended for adult liver transplant patients in combination with reduced dose tacrolimus. Steroid doses may be further tapered on an individualized basis depending on the clinical status of patient and function of graft.
Side effects : Weakness, Sinus inflammation, Infection, Fever, Cough, Fatigue, Stomatitis (Inflammation of the mouth), Otitis media (infection of ear), Diarrhoea, Upper respiratory tract infection.