Edaravone Injection 30 mg is a neurotrophic drug, is prescribed to alleviate the neurological symptoms due to acute cerebral infarction and to improve routine activity and ability. Edaravone is also prescribed to treat functional disorders. Edaravone exerts cerebral protective activity by scavenging free radicals.As a free radical scavenger,Edaravone lowers N- acetyl aspartate (NAA) and reduce cerebral blood flow into the cerebral infarct areas.Edaravone reduces cerebral edema and cerebral infarction and lowers lipid-peroxidation induced neuronal death and subsequent oxidative stress of endothelial cells of the brain.
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Consider administration of 30 mg of Edaravone injection reconstituted with normal saline, two times a day. The course of treatment should be less than 2 weeks. IV infusion of Edaravone should be considered within 24 hours of onset of symptoms.
Hepatic dysfunction, rash, Acute renal failure, nephritic syndrome, hepatitis, jaundice, thrombocytopenia, granulocytopenia, disseminated intravascular coagulation (DIC), acute lung injury, rhabdomyolysls, shock, anaphylactoid reaction etc.Incompatibilities : Edaravone injection should not be administered with infusion of anticonvulsant drugs like diazepam, phenytoin sodium, etc. and not be mixed with potassium canrenoate as the solution may becomes cloudy if administered together.