DigiFab DIGOXIN IMMUNE FAB (OVINE) 40mg Injection

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DESCRIPTION

DigiFab 40mg (DIGOXIN IMMUNE FAB (OVINE))  is used as  an antidote to treat a life-threatening or potentially life-threatening digoxin toxicity or overdose  of digoxin or digitoxin and not used to treat a mild digitalis overdose.

Manufacturer : GlaxoSmithKline

ADDITIONAL INFORMATION

Strengths available :  40mg

Storage : Store at temperature between  2°C – 8°C

Dosage :

Acute ingestion of unknown amounts of digoxin and toxicity in the absence of a serum digitalis concentration or estimated ingestion amount : Administer 20 vials of DigiFab. Monitor for volume overload in small (< 20 Kg) children. Start with 10 vials followed by an additional 10 vials, if needed, to avoid a febrile reaction.

Chronic digoxin toxicity in the absence of a serum digitalis concentration :  Administer 6 vials of DigiFab  in Adults and Children ≥ 20 Kg.

Acute ingestion of known amounts of digoxin : Dose (in vials) = Amount of digoxin ingested (in mg) 0.5 mg/vial

Chronic digoxin toxicity and known serum digitalis concentration : Dose (in vials) = (Serum digoxin ng/mL)(weight in kg) 100

SIDE EFFECTS

Common side effects are signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue,   throat, Signs of low potassium levels, Very bad dizziness, Cough, A fast heartbeat.

PACK SIZE

Pack of 1 vial

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