Chlorambucil is a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia. It is a nitrogen mustard alkylating agent . It also has been used as an immunosuppressive drug for various autoimmune and inflammatory conditions, such as nephrotic syndrome. In India, its manufactured by two companies Natco & Celon. Celon sells it on the brand name of Celkeran 2 mg tablet. Packing is for 30 tabs per pack.
Manufacturer: Celon Labs
Side Effects Include:
GI disturbances; hepatotoxicity; skin rashes; peripheral neuropathy; central neurotoxicity including seizures; interstitial pneumonia, pulmonary fibrosis. High doses may produce azoospermia and amenorrhoea. Sterility when given to boys at or before puberty. Potentially Fatal: Severe bone marrow suppression, carcinogenic and human infertility.