Besponsa Inotuzumab ozogamicin 1 mg

Description

Besponsa is a prescription drug, it is an anti-body conjugate  used to treat refractory B-cell precursor acute lymphoblastic leukemia. To buy Besponsa 1mg or to know its price contact 3S Corporation.    

Manufacturer : Pfizer Inc

Additional Information

Strengths available :  1 mg

Form :  Injection

Dosage : Recommended dose for Lymphoblastic Leukemia – Cycle 1 (total dose is 1.8 mg/m2/cycle):

-Day 1: 0.8 mg/m2 IV

-Day 8: 0.5 mg/m2 IV

-Day 15: 0.5 mg/m2 IV

Duration of therapy: Cycle 1 is 21 days in duration, but may be extended to 28 days (7-day therapy free interval starting on Day 21) if the patient achieves a complete remission (CR) or complete remission with incomplete hematologic recovery (CRi), and/or to allow for recovery from toxicity.

Subsequent Cycles: For patients who achieve a CR or CRi (total dose is 1.5 mg/m2/cycle):

-Day 1: 0.5 mg/m2 IV

-Day 8: 0.5 mg/m2 IV

-Day 15: 0.5 mg/m2 IV

Duration of therapy: 28 days (7-day therapy free interval starting on Day 21) OR

For patients who do not achieve a CR or CRi (total dose is 1.8 mg/m2/cycle):

 -Day 1: 0.8 mg/m2 IV

-Day 8: 0.5 mg/m2 IV

-Day 15: 0.5 mg/m2 IV

Duration of therapy: 28 days (7-day therapy free interval starting on Day 21); patients who do not achieve a CR or CRi within 3 cycles should discontinue therapy

For patients proceeding to hematopoietic stem cell transplant (HSCT):

Duration of therapy: 2 cycles; a third cycle may be considered for those patients who do not achieve CR or CRi and minimal residual disease (MRD) negativity after 2 cycles

For patients not proceeding to HSCT:

-Duration of therapy : Additional cycles of treatment, up to a maximum of 6 cycles, may be administered

Storage : Refrigerate 2°C –8°C

Is the medicine US FDA  approved : Yes

Date of Approval : August 17, 2017

Side Effects

Common side effects are black, tarry stools, bleeding gums, blood in the urine or stools, chest pain, chills, cough or hoarseness, coughing up blood, difficulty in breathing or swallowing, dizziness, fever, headache, increased menstrual flow or vaginal bleeding, lower back or side pain, nosebleeds, painful or difficult urination, pale skin, paralysis, pinpoint red spots on the skin, prolonged bleeding from cuts, red or dark brown urine, sore throat, sores, ulcers, or white spots on the lips or in the mouth, swollen glands, troubled breathing

PACK SIZE

Pack of 1 vial

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