Afinitor 5 mg tablets from Novartis also known as ‘Everolimus’ is a FDA approved drug to treat the following diseases.
1.Advanced hormone receptor-positive, HER2-negative breast cancer, along with the medicine exemestane, in postmenopausal women who have received certain other medicines for their cancer.
2.Adults with pancreatic neuroendocrine tumor (PNET) that has progressed and cannot be treated with surgery.
Adults with advanced kidney cancer (renal cell carcinoma or RCC)
3.Adults with a kidney tumor called angiomyolipoma, seen with a genetic condition called tuberous sclerosis complex (TSC), when their kidney tumor does not require surgery.
Common side effects while taking Afinitor include mouth ulcers. Tell your healthcare provider if you have pain, discomfort, or open sores in your mouth. Your healthcare provider may tell you to use a special mouthwash or gel that does not contain alcohol, peroxide, iodine, or thyme.
Other common side effects include:
- Feeling weak or tired
- Cough, shortness of breath
- Diarrhea and constipation
- Skin problems (such as rash, acne, dry skin, or itching)
- Nausea and vomiting
- Loss of appetite, weight loss
- Swelling of arms, hands, feet, ankles, face, or other parts of the body
- Abnormal taste or dry mouth
- Inflammation of the lining of the digestive system
- Nose bleeds
- Absence of menstrual periods. You may miss one or more menstrual periods. Tell your healthcare provider if this happens
- Pain in arms and legs, mouth and throat, back or joints, or stomach area (abdomen)
- Low red blood cells, white blood cells, or platelets
- Increased blood cholesterol level and certain other blood tests
- Decreased blood phosphate level
- Increased blood sugar levels
- High blood pressure
- Difficulty sleeping
- Hair loss
- Muscle spasms
- Feeling dizzy
- Nail disorders
- Anxiety, aggression, and other abnormal behaviors