Palbace ( known as IBRANCE in other parts of the world) or palbociclib by Pfizer is a cancer drug that interferes with the growth and spread of cancer cells in the body.
Palbace is generally used in combination with letrozole or fulvestrant (Faslodex) for treating certain types of advanced breast cancer in postmenopausal women. It is also given in combination with another cancer medicine, either letrozole (Femara) or fulvestrant (Faslodex).
Palbace is a renamed version of the drug Ibrance for the Indian market. It is approved by the US Food and Drug Administration (FDA). In clinical studies, palbociclib appeared to improve survival time of patients.
Palbace comes in capsule form in 125 mg dose. 1 pack has 21 capsules.
Common side effects of IBRANCE include:
Low red blood cell counts and low platelet counts. Call your healthcare provider right away if you develop any of these symptoms during treatment:
shortness of breath
bleeding or bruising more easily
hair thinning or hair loss
loss of appetite
IBRANCE may cause fertility problems in males. This may affect your ability to father a child. Talk to your healthcare provider if this is a concern for you.
These are not all of the possible side effects of IBRANCE. For more information, ask your healthcare provider. Tell your healthcare provider if you have any side effect that bothers you or does not go away.
Tell your healthcare provider about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. IBRANCE and other medicines may affect each other, causing side effects. Tell your healthcare provider if you start a new medicine.
Take IBRANCE exactly as your healthcare provider tells you.
Take IBRANCE capsules with food and swallow the capsules whole. Do not chew, crush, or open IBRANCE capsules before swallowing them. Do not take any IBRANCE capsules that are broken, cracked, or that look damaged. If you miss a day’s dose or vomit after taking a dose of IBRANCE, do not take an extra dose; just take your next dose at your regular time. Do not drink grapefruit juice or eat grapefruit products while taking IBRANCE. Grapefruit or grapefruit juice may increase the amount of IBRANCE in your blood.
If you take too much IBRANCE, call your healthcare provider right away or go to the nearest hospital emergency room.