Noxafil ( generic name posaconazole) is an antifungal medicine manufactured by Merck which fights certain infections caused by fungus. It is used to prevent fungal infections in people with weak immune systems resulting from certain treatments or conditions including chemotherapy, stem cell transplantation, HIV infection and others. Noxafil is also used to treat oral thrush (yeast infection of the mouth). It comes in 200 mg/ 5ml (40 mg per ml) in 105 ml.
Noxafil injection must be administered through an in-line filter. Administer by intravenous infusion over approximately 90 minutes via a central venous line. Never give Noxafil injection as an intravenous bolus injection.
Common treatment-emergent adverse reactions in studies with posaconazole are diarrhea, nausea, fever, vomiting, headache,
coughing, and hypokalemia.