DARZALEX Daratumumab 100mg & 400mg Injection

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DESCRIPTION

DARZALEX (daratumumab) is a monoclonal antibody used to treat multiple myeloma.  It  works in your body  by attaching itself to multiple myeloma cells and directly kills them, thereby allows your immune system to destroy them. Darzalex is a prescription drug.

Manufacturer :  Janssen Biotech Inc.

ADDITIONAL INFORMATION

Strengths available :  100mg/5ml & 400mg/20ml

Storage : Store at temperature between 2 °C to 8 °C

It is US FDA approved

Dosage :

Multiple Myeloma (Monotherapy) 

  • Indicated as monotherapy for multiple myeloma in patients who have received at least 3 lines of therapy, including a proteasome inhibitor (PI) and an immunomodulatory agent (IMiD), or who are double-refractory to a PI and IMiD
  • Weeks 1-8: 16 mg/kg IV infusion once weekly
  • Weeks 9-24: 16 mg/kg IV infusion every 2 weeks
  • Week 25 onward until disease progression: 16 mg/kg IV infusion every 4 weeks

SIDE EFFECTS

Most common side effects are tiredness, nausea, diarrhea, constipation, vomiting, muscle spasms, joint pain, back pain, fever, chills, dizziness, insomnia, cough, shortness of breath, swollen hands, ankles or feet, nerve damage causing tingling, numbness or pain, cold-like symptoms (upper respiratory infection).

PACK SIZE

Pack of 1 Vial

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